Forskolin is a compound found in the roots of an herbal plant called Plectranthus barbatus, which belongs to the mint family. It has been used by our ancestors to treat a number of conditions and as it is a natural source, it does not pose any risk to the user.

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Forskolin is also Known as:

  • HL-362
  • Plectranthus Barbatus
  • L-75-1362B
  • Forskoline
  • Forskolina
  • Forsolin
  • Forskohlii
  • Colforsine
  • Colforsin
  • Coleus Forscohlii
  • Coleus Barbatus
  • Coleus
  • Borforsin
  • 6beta
  • 13-epoxy-1alpha
  • 17beta-acetoxy-8

Forskolin extract works on the heart muscles and on the walls of the blood vessels thereby widening it. This lowers blood pressure and produces powerful heartbeat.

Interactions with Other Medicines

  • Forskolin can lower blood pressure, so avoid taking this supplement along with medicines for high BP, which can decrease blood pressure. The medications for high BP include amlodipine, felodipine, isradipine, diltiazem, verapamil, nifedipine.
  • Taking forskolin along with medicines, which increase the flow of blood to the heart, might cause lightheadedness and dizziness. So, don’t use this supplement, if you are under any medications, which increase blood flow to your heart. Isosorbide, nitroglycerin are some of the medications that enhance the blood flow.
  • As forskolin slows down blood clotting, taking it along with medicines that slows clotting will increase the risk of bleeding and bruising. Dalteparin, enoxaparin, ibuprofen, diclofenac, clopidogrel, and aspirin are some of the medications that can slow down blood clotting.

Dosage Considerations

It is safe for adults when appropriate dosage is taken through inhalation, eye drops or injection. The following doses are studied under scientific research.

Inhalation: Healthcare providers give individuals with asthma problem breath in the powder of forskolin with the help of a spinhaler inhalator.

Intravenous: Under medical supervision, forskolin was given intravenously for the heart ailment known as idiopathic congestive cardiopathy.

Avoid using Forskolin if:

  • You have blood pressure and cardiovascular problems
  • During pregnancy or breast-feeding
  • If you are undergoing any surgical procedure in the next few weeks, as forskolin has a tendency to increase the perils of bleeding.
  • If you have a condition, which is likely to cause bleeding

Scientific Studies

Human studies were conducted to know the effect of Coleus Forskohii, which included placebo controlled and double blind clinical trials. The results on some of the conditions are as follows:

  • Asthma – It appeared to be effective in suppressing asthmatic signs than other nutraceuticals.
  • Weight – Mixed effects and it appears to be quite effective in men than in women
  • Blood Pressure – No considerable influence was noted in blood pressure with the supplementation of coleus
  • Fatigue – Less fatigue was reported as a side effect.
  • Intraocular Pressure – It was fairly effective in reducing ocular pressure with ocular eye drops
  • Testosterone – Testosterone increase was observed in men, which was not overly potent.
  • Lean Mass – Somewhat effective, confounded with an increase in bone mass. The lean mass includes skeletal muscle and bone
  • HDL-C – The increase was remarkable, but needs further study with larger trials.

Fat Mass – Effective in decreasing fat mass in overweight and obese people